.

Tuesday, March 5, 2019

Determination of the vitamin D status of adults living in the UK and identification of factors influencing the efficacy of dietary intervention

Introduction at that place is oerwhelming clinical demonstrations that vitamin D plays a significant role in terms of the modal(prenominal) functioning of human body. One of the most joints functions of vitamin D is to ensure normalcy in detecting blood levels of some(prenominal) calcium and phosphate. The two ele handsts atomic number 18 essential for normal off-white mineralisation, contraction of muscles, conductivity of nerves, and other general body cellular functions. As much(prenominal), wish of vitamin D is associated with various adverse health complications including failure in proper bone development, cancer, and heart diseases (Holick, 2011, p.6). A review of several studies has in any case established evidence that vitamin D replacement can boots enormousevity among other health benefits (Gaddipati, et al. 2010). able synthesis of vitamin D3 from the skin, everyday diet and supplements is essential for health of bones. In rundown to the well-known role of v itamin D in regulating calcium metabolism, active voice form of vitamin D is also associated with anti-proliferative as well as immunomodulatory effects that argon linked to several serious conditions such as cancer, metabolic syndrome, cardiovascular diseases, obesity, diabetes, tuberculosis, dementia among other illnesses (Zitterman,et al., 2001).There wee-wee been concerns that vitamin D inadequateness is significantly increasing in the western nations, and the likelihood of the problem worthy an epidemic in itself worries nutritionists as well as medical practitioners likewise (Hypponen and Power (2007). A recent survey in England has revealed a deplorable statistics that half of the adult tribe does non book sufficient levels of vitamin D (Pearce and Cheetham, 2010). The similar select also revealed that 16% of this population has experienced arrant(a) hypovitaminosis D during winter and spring, with the highest commit being residents of Northern England areas. I t is perhaps unsurprising that thither have been increasing calls for regular screening during normal health care services. The concerns over vitamin D deficiency has led to a shift over the past decade, with several researchers striving to establish or so of the most common risk factors associated with vitamin D deficiency (Holick, 2004).In a study to establish difference in propensity to vitamin D deficiency between metabolically health and unhealthy obese adults, Esteghamati et al. (2004) found emerge that metabolically healthy obese registered more(prenominal) absorption of vitamin D than metabolically unhealthy obese. This difference persisted even after accounting for body view index (BMI) and circumference of the individuals waists. Further, there was significantly better metabolic attitude and higher concentration of serum 25-hydro vitamin D among the subjects with metabolically healthy obesity. The researchers also noted that the metabolically unhealthy subjects had higher concentrations of liver enzymes and subversive markers. In February 2014, health & Social Care Information centre released a bill on obesity, physical activity, and diet in England, which indicated that obesity cases were on the splay (HSCIC, 2014). The data indicate that there has been a significant increase in the proportion of obese population from 13.2 percent in 1993 to 24.4 percent of men in 2012. Women recorded a similarly high increase during the same period from 16.4 percent to 25.1 percent. Linking this data to relationship between obesity and vitamin D deficiency, it prudent to highlight that vitamin D deficiency prevalence is a bakshish researchers should note with keenness it deserves. The extent to which vitamin D deficiency is a existence health problem in Britain is believed to have increased for several reasons ranging from modus vivendi to weather patterns. On lifestyle as a factor, Hypponen and Power (2007) states that the sedentary lifestyle in the western world, including Great Britain, leads to vitamin D deficiency, which is exacerbated by a number of other factors including working deep down during daylight hours, high parallel of latitude and a mostly cloudy climate in regions such as Manchester. Statistics also indicate that vitamin D dietetic intake is much pooh-pooh in Great Britain compared to other western nations including join States and Canada (Calvo et al, 2005, p.314). The variance in dietary intake of vitamin D between Britain, on the one hand, and United States and Canada, on the other, may be due to the mandatory fortification of both milk and margarine in the USA and Canada. Some of the most common food sources rich in vitamin are tip, liver, beef up margarine and fortified cereals. However, clinical nutritional assessments of natural food items suggest that with the exception of seek and cod liver oil, most natural food stuff contains stripped vitamin D, if any (Brough et al., 2010). Significantl y, it is important to note that insufficient natural sources for vitamin D is a risk factor in itself, and should be taken into consideration when plans are put into place to tackle the problem. Moreover, vitamin D supplements availability cannot be set forth as reliable since demand always exceeds supply (Brough et al., 2010). Studies have revealed that there are high wanders of vitamin D deficiency all over Great Britain, curiously in the cloudy regions like Manchester and Scotland (Pal et al., 2003). Obesity is a well-known risk factor for vitamin D deficiency, and its high prevalence in Great Britain is likely to affect vitamin D berth in the population of forged regions such as Greater Manchester. In another countrywide study conducted to investigate the demographic characteristics of white population and possibility of supplements use, it emerged that women and non-obese participants were more likely to use vitamin D supplements (Gaddipati et al, 2010). Similarly, residen ts of Northern England were found to consume little oily fish, an important source of vitamin D, compared to their Southern counterparts. The study concurs with tells that people life history on the Northern England and Scotland have higher risk of hypovitaminosis D (Roy et al., 2007 Holick, 2004). In fact, those who are obese and also live in spoiled regions have a likelihood of having vitamin D deficiency twice as high as other obese people living in other areas of Great Britain.Vitamin D deficiency has also been reported to be general among minority communities living in Great Britain (de Roos et al, 2012). Some cultural minorities living in Great Britain are more susceptible to vitamin D deficiency than other groups. According to Brough et al. (2010), minority ethnic communities, particularly those who ghostwriter their roots to Indian subcontinent and Africa as they tend to suffer from rise in skin pigmentation. They are also found to increase their susceptibility to vit amin D deficiency by wearing clothes that tend to cover their faultless bodies and staying indoors longer hours during the day (de Roos et al, 2012 Brough et al., 2010). Other researchers recognise the postulate to increase vitamin D supplement intake among the minority population, amid report that there are no consistent or routine supply of vitamin D uncomplete are there recognised screening programs targeting this group (Dealberto, 2006).A study looking at population demographics in the North wolfram has revealed that the region has increasing number older people (North westbound Regional accumulation give notice (of), 2000). As stated earlier, elderly people are at high-risk of vitamin D deficiency. Clinical studies have investigated age-related decline in vitamin D intake, including rate of skin absorption and response to targeted methods of increasing vitamin D through dietary interventions (Shaw and Pal, 2002). Several other studies have also linked low vitamin D statu s with people living in low economic status (Dealberto, 2006.). In many of these linkages, the authors cite issues such as myopic nutrition, poor lifestyle and inability to dedicate supplements. For instance, poor nutrition intake is prevalent in regions with high poverty rate, mostly affecting middle vulcanized women of child-bearing age (Brough et al., 2010). According to Brough et al. (2010) a socially deprived population cannot afford some of the basic nutrients essential for normal metabolic function such as vitamin D and thus resort to shortcuts of life while exposing their resistant system to chronic diseases. mendicancy report released by the Greater Manchester Poverty Commission in 2002 identified Manchester as one of the regions with the highest cases of extreme poverty, with 25 percent of its population living in abject poverty (GMPC, 2012). The report further reveal that poor families cannot protect themselves from winter temperature, which makes them stay indoors lo nger than other UK residence with average annual income. This can plainly mean that they have higher risk from vitamin D deficiency. OECD report (2014) suggests that the early step in ensuring low income community members in the United ground are protected from lifestyle related diseases is through social interventions.Tests have revealed that modest rise in vitamin D intake of up to 20 g per day for this group can significantly reduce the rate of bone fracture (Hypponen and Power, 2007). The findings have raised focus by agencies and researchers, who have recommended that vitamin D intake for the elderly should raised from the live 5g per day to between 10-20g per day in order to maintain the normal hydroxy vitamin D of 25 (de Roos, 2012, p.6).Considering the need to increase vitamin D intake among the population at risk of vitamin D deficiency, the UK Committee on Medical Aspects of Food Policy (COMA) recommended that people eat at to the lowest degree 280 g of fish per week, with preference to oily fish (de Roos, Sneddon and Macdonald, 2012, p.6). The Scientific advisory Committee on Nutrition (SACN) endorsed the COMA recommendation, emphasising that this is the bare minimum fish exercise recommended for the average population goal to achieve the desired vitamin D status. However, they acknowledged that this recommendation does not represent the level of fish consumption required for optimal nutritional benefits. The campaign to encourage more UK population, particularly those living in North Western region, should be directed at increasing oily fish intake by at least 280 g per week as statistics indicate that majority of them do not consume enough fish (de Roos, 2012 Holick, 2011 Hypponen and Power, 2007).Although studies (de Roos, 2012 Holick, 2004) have dwelt on the need for five-fold interventions ranging from dietary to medical, of more significant for the efficacy of dietary intervention is the need for education among the population on the i mportance of adopting healthy diet and lifestyle. This is mostly recommended for the high-risk persons including the low-income population, those living in marginally wet and cloudy regions including Manchester, obese, and unfledged women of child bearing age group.ReferencesBrough. L., Rees, G., Crawford, M.A. Morton. R.H. and Dorman, E.K. 2010. Effect ofmultiple- micronutrient supplement on parental nutrient status, infant birth weight and gestational age at birth in a low-income, multi-ethnic population. British Journal of Nutrition, 104 (3) 437- 445.Calvo, M.S., Whiting, S.J. and Barton, C.N. 2005. Vitamin D intake a global perspective ofcurrent status. J Nutr one hundred thirty-five 3106.de Roos, B. Sneddon, A. and Macdonald, H. 2012. Fish as a dietary source of healthy long chainn-3 polyunsaturated fatty acids (LC n-3 PUFA) and vitamin D A review of current literature. Food & Health Innovation Service, available at http//www.abdn.ac.uk/rowett/documents/fish_final_june_2012. pdf.Dealberto, M.J. 2006. Why immigrants at increased risk for psychosisVitamin D insuffiency,epigenetic mechanisms, or bothMedical Hypothesis, Vol. 68, pp. 259- 267.Esteghamati, A., Aryan, Z. and Nakhjavani, M. 2004. Differences in vitamin D concentrationbetween metabolically healthy and unhealthy obese adults Association with inflammatory and cardiometabolic markers in 4391 subjects. Diabetes & Metabolism, 5 whitethorn 2014, Available online at http//www.sciencedirect.com/science/ hold/pii/S1262363614000469Gaddipati, V.C., Kuriacose, R. and Copeland R., et al. 2010. Vitamin D deficiency an increasingconcern in peripheral arterial disease. J Am Med Dir Assoc. 11(5) 308-11.Greater Manchester Poverty Commission (GMPC). 2012. Research Report . The Centre forLocal Economic Strategies.Holick, M.F. 2011. Vitamin D a d-lightful solution for health. J Investig Med. 59(6)872-80.Holick MF. 2004. Sunlight and vitamin D for bone health and prevention of autoimmunediseases, cancers, and cardiov ascular disease. Am J Clin Nutr 80 (suppl)1678S88S.HSCIC. 2014. Statistics on Obesity, physical Activity and Diet. Health & Social CareInformation Centre, England 26 February 2014.Hypponen, E. and Power, C. 2007. Hypovitaminosis D in British adults at age 45 y nationwideage bracket study of dietary and lifestyle predictors. Am J Clin Nutr, 85(3) 860-868.North West Regional Assembly, 2000. An Aging Population Impact for the North West. NorthWest Regional Laboratory. Lancaster University. Available at www.northest-england.org.uk.OECD Report. (2014). Society at a glimpse 2014 Highlights United Kingdom OECD SocialIndicators. Last accessed on 19 May 2014 at http//www.oecd.org/unitedkingdom/OECD-SocietyAtaGlance2014-Highlights-UnitedKingdom.pdfPal , B.R., Marshall ,T. and James, C. 2003. Shaw NJ. Distribution analysis of vitamin Dhighlights differences in population subgroups preliminary observations from a pilot study in UK adults. J Endocrinol. 17911929.Pearce, S.H. and Cheetham, T.D. J anuary, 2010. Diagnosis and management of Vitamin Ddeficiency. BMJ, 11 340.Roy D.K, Berry J.L., Pye, SR et al. 2007. Vitamin D status and bone mass in UK South Asiawomen. Bone 40(1) 200-4. Epub 2006 folk 6.Shaw, N.J and Pal, B.R. 2002. Vitamin D deficiency in UK Asian families activating a spic-and-spanconcern. Arch Dis Child, 86 147-149, Available at http//adc.bmj.com/content/86/3/147.fullZittermann A, Schleithoff SS, Koerfer R. 2005. Putting cardiovascular disease and vitamin Dinsufficiency into perspective. Br J Nutr 94 48392.

No comments:

Post a Comment